KMID : 0545119970070060429
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Journal of Microbiology and Biotechnology 1997 Volume.7 No. 6 p.429 ~ p.434
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Neuronal Cell Protection Activity of Macrolactin A Produced by Actinomadura sp.
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Kim, Hyeon Ho
Kim, Won Gon/Ryoo, In Ja/Kim, Chang Jin/Suk, Jae Eun/Han, Kyou Hoon/Hwang, Se Young
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Abstract
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Macrolactin A, 24-membered macrolide, was isolated from the culture broth of Actinomadura sp. as a neuronal cell protecting substance. In the cell assay, this compound inhibited glutamate toxicity in N18RE-105 cells with an EC_50 value of 0.5 §¶/§¢.
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